2021/7/20
Viral infection is a serious challenge faced by humanity, especially in recent years when the situation of hospital infection control has become severe and the outbreak of new viral infections has made effective control of virus transmission and infection increasingly important. The research and use of disinfection methods is an important means to prevent the spread and infection of viruses. There are many types of comprehensive disinfection methods for virus laboratory space disinfection environment, and they are constantly changing. The accompanying problem is what kind of sterilization method is the ideal sterilization method for enclosed sterile room space.
The virus laboratory is a highly secure laboratory used for virus research, protecting personnel safety, and preventing the spread of viruses into society. The disinfection and sterilization work after the experiment is essential. How to effectively, quickly, residue free, and safely disinfect and find solutions for each virus laboratory manager.
The P4 laboratory is a high level of biological safety protection laboratory that humans have been able to build so far, suitable for the research of pathogenic microorganisms and their toxins that pose a high risk to human health, are transmitted through aerosol routes or have unknown transmission routes, and currently have no effective vaccines or treatment methods. Only a few developed countries in the world have such devices.
The structure of the P4 laboratory can be roughly described as follows: the entire laboratory is a suspended structure, divided into 4 floors. From bottom to top, the bottom layer consists of sewage treatment and life support systems; The second floor is the core laboratory; The third layer is the filter system; The interlayer between the second and third floors is the piping system; The upper level is the air conditioning system. All the first, third, fourth, and middle floors are designed to ensure the normal operation of the second floor core laboratory, creating a unidirectional airflow and negative pressure inside the laboratory. The contents inside cannot come out, only the outside can enter, like a sealed box.
According to relevant reports, a Japanese professor has developed a super influenza virus that, once leaked, will be "unsolvable" and cause controversy among humans; An anthrax virus leak occurred in a laboratory in the United States, triggering a crisis. Global laboratory virus leakage incidents occur from time to time, with the United States experiencing over 600 virus leaks in the past seven years.
In September 2003, a graduate student at the National University of Singapore was infected with SARS virus in the laboratory of the Institute of Environmental Health. The graduate student was confirmed to be infected with SARS when he went to Singapore Central Hospital for treatment due to fever, and had previously had contact with multiple people.
In December 2003, a SARS researcher in Taiwan was infected with the SARS virus in the laboratory.
In April 2004, new cases of SARS were discovered in Anhui and Beijing respectively, which were confirmed to be from two staff members infected with SARS in the laboratory of the Chinese Institute for Disease Control and Prevention.
On April 13, 2005, the World Health Organization issued an alert to thousands of laboratories in 18 countries worldwide to immediately destroy H2N2 influenza virus samples. To prevent a large-scale outbreak of influenza, the laboratories of the relevant countries immediately raced against time upon receiving the report and quickly launched the operation to destroy the H2N2 influenza virus.
It is urgent to choose reasonable and rapid emergency response or ideal space sterilization measures for the safety protection of virus laboratories. Ozone disinfection has limited ability, while ultraviolet lamps have many disadvantages that cannot meet the requirements. Only disinfection measures that truly reach the sterilization level are effective. Portable, remotely controllable, automatic space sterilization, comprehensive space gas fumigation sterilization without dead corners to eliminate infectious viruses, replacing the traditional cumbersome and complex harmful formaldehyde fumigation, the most suitable is the vaporized hydrogen peroxide sterilizer.
The vaporized hydrogen peroxide sterilization technology uses flash evaporation technology to drop high concentration hydrogen peroxide solution (usually 30% higher in concentration) onto the surface of a heated smooth metal object, causing it to vaporize instantly. At present, the vaporization hydrogen peroxide sterilization method has become a pharmacopoeia of various countries GMP、 The recommended methods for disinfection and sterilization technology specifications have a mature sterilization process with good repeatability. There are specialized chemical and biological indicators to verify the uniform distribution and sterility level of hydrogen peroxide gas. It can be widely applied in many fields such as biopharmaceutical factories, healthcare, biological laboratories, and animal research laboratories.
The TL-V500 integrates the function of intelligent remote control, enabling real-time monitoring of humidity and temperature within the sterilization space, and has relatively low requirements for the environment of the sterilization space. It features a split control system, making it suitable for sterilization in various complex environments. It has two built-in modes: scattering and pipeline transportation. The low-temperature sterilization process can be carried out at room temperature. It starts quickly and can achieve rapid disinfection and sterilization. Adding hydrogen peroxide solution is convenient and safe. The sterilization time is short and the operating cost is low. Hydrogen peroxide gas has good material compatibility and is highly compatible with plastics, rubber, and electronic products. It has a broad-spectrum sterilization effect, with a killing ability of 106 for thermophilic spores. It is equipped with a Siemens control system, featuring data export of sterilization process records, intelligent networking and other expandable functions. Network connection or wired connection is optional.
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